Best Vitamin D3 and K2 Supplements for True Health Enthusiasts

Last updated on May 13th, 2024 at 06:10 pm

In the realm of health and wellness, few nutrients have garnered as much attention as vitamins D3 and K2. These essential vitamins play important roles in maintaining overall longevity, from supporting bone strength to promoting cardiovascular well-being.

Vitamin D3, also known as the “sunshine vitamin,” is crucial for calcium absorption and bone mineralization, helping to prevent osteoporosis and fractures(1). It also modulates immune function, enhances mood regulation, and contributes to muscle strength(2, 3, 4).

Also vital for health, vitamin K2 plays an important role in blood clotting(5). The nutrient protects the health of your heart and helps keep your bones strong(6, 7).

When taken together, vitamins D3 and K2 form a partnership that optimizes various aspects of wellness. While vitamin D3 enhances calcium absorption, vitamin K2 ensures this mineral is directed to the bones and teeth rather than accumulating in the soft tissues or arterial walls.

This process not only helps to promote bone health but also keeps your heart healthy.

As our awareness of the importance of these vitamins grows, so does the market for supplements aiming to fulfill our bodies’ nutritional requirements. 

For true health enthusiasts committed to maximizing their well-being, selecting the right vitamin D3 + K2 product is crucial. With such a wide range of options available, navigating them can be overwhelming.

To help you in your health journey, we’ll unveil our top vitamin D3 + K2 picks in this comprehensive guide. We’ll explore the key factors to consider when choosing your product, including potency, bioavailability, and potential synergistic effects.

Whether you’re seeking to optimize your bone health, support your immune system, or enhance your cardiovascular wellness, this article aims to empower you with the knowledge you need to make informed decisions about your supplement regimen.

Let’s get to it.

1. Nutridyn D3 5000 with K2

Dosage1 softgel daily
Vitamin D3 per dose125 mcg (5,000 IU)
Vitamin K2 per dose60 mcg

Nutridyn D3 5000 with K2 is the ideal supplement for those looking to improve their immune system health, cardiovascular function, and the strength and stability of their bones.

It contains highly bioavailable vitamin D3 in the form of cholecalciferol, along with vitamin K2 as patented MenaQ7. This powerful combination of nutrients aids in preventing nutritional deficiencies that can affect a variety of bodily systems.

Athletes have reported Nutridyn’s D3 and K2 combination as especially effective at enhancing their performance and recovery. The potent ingredients support overall bone health, which is crucial for sportspeople to withstand the physical demands of training and competition.

D3 5000 with K2 comes in small, easy-to-swallow softgels that make supplementation hassle-free. These compact capsules are designed for effortless incorporation into daily routines, allowing you to meet your daily vitamin D3 and K2 needs without any inconvenience.

2. NOW Clinical Cardio

Dosage1 capsule twice daily
Vitamin D3 per dose25 mcg
Vitamin K2 per dose70 mcg

NOW Clinical Cardio contains a powerful combination of targeted botanicals that are known to promote cardiovascular health. 

While L-carnitine and Coenzyme Q10 support energy production in the heart, hawthorn and grape seed extract work to keep blood pressure within the normal range. The formulation also includes vitamin K2 as MK-7, which helps to maintain arterial flexibility.

With 25 mcg of vitamin D3 as cholecalciferol, Clinical Cardio offers a potent dose of the essential nutrient to also support bone health and immune function.

This comprehensive formula forms an essential part of any approach to a healthy heart, helping you to optimize your cardiovascular wellness and promote overall well-being.

3. Nutridyn D3 10,000 with K2

Dosage1 softgel daily
Vitamin D3 per dose250 mcg (10,000 IU)
Vitamin K2 per dose137 mcg

NutriDyn D3 10,000 with K2 combines a highly bioavailable form of vitamin D3 with vitamin K2. This potent formula is designed to maintain healthy vitamin D levels which in turn help support bone, heart, immune system, and brain health.

This supplement includes 250 mcg of vitamin D3 in each dose, ensuring that you receive a potent and effective amount of the essential nutrient to address any deficiencies and support optimal health.

With such a significant dosage, Nutridyn D3 10,000 with K2 offers a convenient solution for those with increased vitamin D requirements, like individuals with limited sun exposure or certain health conditions.

4. S Raw Science Vitamins K2 + D3 Drops

Dosage2 drops daily
Vitamin D3 per dose250 mcg
Vitamin K2 per dose200 mcg

S Raw Science Vitamins K2 + D3 Drops is an innovative blend that supports immune health, fortifies bones, and promotes heart and brain function.

Ideal for those wanting to optimize total body wellness, these unique drops contain 250 mcg of vitamin D3 in each dose to promote calcium absorption for healthy bones and teeth. They also offer 200 mcg of vitamin K2 for effective calcium management.

Formulated for maximum absorption, S Raw Science Vitamins K2 + D3 drops’ liquid formulation simplifies taking your daily supplements, ensuring rapid assimilation and bioavailability for enhanced effectiveness and convenience.

This offering shines for its commitment to purity. Free from any unnecessary additives, these drops align with diverse dietary needs and provide peace of mind for those seeking a clean supplementation option, further enhancing their appeal among health-conscious buyers.  

5. Ortho Molecular Vitamin K2 with D3

Dosage1 capsule daily
Vitamin D3 per dose125 mcg (5,000 IU)
Vitamin K2 per dose45 mcg

Ortho Molecular Vitamin K2 with D3 can help promote bone health and maintain cardiometabolic function. 

Its unique formulation, which includes synergistic doses of vitamin K2 as MK-7 and vitamin D3, offers comprehensive support for calcium metabolism. This ensures optimal bone mineralization and reduces the risk of osteoporosis and fractures.

Ortho Molecular Vitamin K2 with D3 contains bioavailable forms of these vitamins, enhancing absorption and efficacy.

By choosing this product, you can feel confident in your efforts to support skeletal and cardiovascular health, empowering you to lead an active and vibrant lifestyle.

6. Xymogen K2-D3 5000

Dosage1 capsule daily
Vitamin D3 per dose125 mcg (5,000 IU)
Vitamin K2 per dose90 mcg

Xymogen K2-D3 5000 features the most bioavailable and bioactive form of vitamin K2 available. It also contains vitamin D3 as cholecalciferol, ensuring optimal absorption and utilization by the body.

This potent combination supports not only bone health but also cardiovascular function, immune system modulation, and overall well-being.

With Xymogen K2-D3 5000, individuals can confidently supplement with these crucial vitamins, knowing they are receiving the highest quality of ingredients backed by scientific research.

This product is also formulated to be free of any allergens and undergoes rigorous quality assurance through third-party laboratory testing to ensure that what it says on the label is inside the bottle.

7. Nordic Naturals Vitamin D3 + K2 Gummies

Dosage1 gummy daily
Vitamin D3 per dose25 mcg (1,000 IU)
Vitamin K2 per dose45 mcg

Nordic Naturals Vitamin D3 + K2 gummies are seriously flavorful, and combine vitamin D3 and vitamin K2 to support healthy bones and your body’s calcium balance.

Containing 1,000 IU of vitamin D3 as cholecalciferol and 45 mcg of vitamin K2 in each serving, these gummies provide delicious and convenient support for bone health, cardiovascular function, and immune system modulation.

Their combination of vitamins ensures optimal absorption and utilization, promoting calcium metabolism and directing it to the bones while preventing arterial calcification.

With their great taste and easy-to-use format, Nordic Naturals Vitamin D3 + K2 gummies are an ideal choice for maintaining strong bones and overall well-being without compromising on flavor or convenience. 

8. Douglas Labs Liquid D and K

Dosage1 dropper daily
Vitamin D3 per dose25 mcg (1,000 IU)
Vitamin K2 per dose1,045 mcg

Douglas Labs Liquid D and K is a natural vitamin D and K supplement that provides natural bone health support. This unique, great-tasting vanilla liquid supplies significant amounts of the vitamins to support cardiovascular wellness.

Its innovative liquid formulation offers rapid absorption, making it an ideal choice for individuals with difficulty swallowing pills or those who prefer liquid supplements.

Douglas Labs Liquid D and K is renowned for its purity and potency and is free from any artificial colors, flavors, and preservatives.

With each serving, you can easily attain your recommended daily dose of vitamins D and K, ensuring comprehensive support for your overall well-being.

9. Metagenics D3 5,000 + K

Dosage1 softgel daily
Vitamin D3 per dose125 mcg (5,000 IU)
Vitamin K2 per dose90 mcg

Metagenics D3 5,000 + K provides 5,000 IU of vitamin D3 per capsule. This high-potency formula also includes a bioavailable form of vitamin K2 to complement the vitamin D.

It comes in easy-to-swallow softgels, with vitamin D solubilized in oil to support absorption in the intestinal tract. This innovative formulation ensures efficient delivery of these essential nutrients to promote optimal health.

With Metagenics D3 5,000 + K, you can confidently support your overall well-being with a convenient and effective supplement.

Empower Your Health Journey

In the pursuit of optimal health, the importance of supplementing your diet with vitamins D3 and K2 can’t be overstated. As we’ve explored the diverse array of options available, from potent capsules to delicious gummies and innovative liquid formulations, it’s evident there’s a perfect fit for everyone’s needs and preferences.

By incorporating the correct vitamin D3 and K2 supplement into your daily routine, you’re not just investing in bone strength or cardiovascular wellness, but also your overall vitality. These essential nutrients work together to support various aspects of your health.

If you have any further questions on how to empower your health journey with vitamin D3 and K2 supplements, feel free to contact us. Our friendly team of experts is here to help you navigate the world of supplementation and provide personalized guidance and support. 










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Medically reviewed by Dr. Jamy Antoine, D.C. — by Chris Bowman — On May 9, 2024


Chris Bowman

Chris Bowman is the CEO and Co-Founder of and has over 15 years of experience in nutritional sciences and wellness. Simply Nutrients is a part of Dr. Jamy Antoine's Select Health Practice in Edina, Minnesota. Chris is passionate about helping people live healthier lives by using the best practices of nature, nutrition, and medicine.